| FT | SSC Napoli | 4-2 |
AFC Ajax |
| 4 | Hirving Lozano | 1 - 0 | |
| 16 | Giacomo Raspadori | 2 - 0 | |
| 27 | 2 - 0 | Kenneth Taylor | |
| 33 | 2 - 0 | Jorge Sánchez | |
| HT | 2 - 0 | ||
| 49 | 2 - 1 | Davy Klaassen | |
| 52 | 2 - 1 | Edson Álvarez | |
| 61 | 2 - 1 | Jurrien Timber | |
| 62 | Khvicha Kvaratskhelia | 3 - 1 | |
| 66 | 3 - 1 | Calvin Bassey | |
| 76 | 3 - 1 | Steven Bergwijn | |
| 83 | 3 - 2 | Steven Bergwijn | |
| 87 | Juan Jesus | 3 - 2 | |
| 89 | Victor Osimhen | 4 - 2 | |
| 90+1 | Victor Osimhen | 4 - 2 | |
| 90+2 | Matteo Politano | 4 - 2 | |
| FT | 4 - 2 |